Epithalon is supplied as a catalogued research material in 10mg and 50mg.
Epithalon/Epitalon denotes the synthetic AEDG tetrapeptide. It must not be confused with Epithalamin, a biologically derived pineal extract used in separate publications. Registry data shown here remain conditional on confirmation of the exact batch form [1–3].
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | Epitalon, AEDG, L-Alanyl-L-alpha-glutamyl-L-alpha-aspartylglycine |
| Material category | Geroprotective Peptide |
| Sequence | H-Ala-Glu-Asp-Gly-OH |
| Molecular formula | C14H22N4O9 |
| Average molecular mass | 390.35 g/mol |
| CAS Registry Number | 307297-39-8 |
| PubChem CID | CID 159235 |
| Structural features | Linear tetrapeptide. |
| Appearance | White to off-white lyophilised powder |
| Solubility | Readily soluble in water. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.
Synthetic tetrapeptide corresponding to a peptide isolated from the pineal gland (Epithalamin).
Research background and published evidence
Published research
Published AEDG research includes an in-vitro study of telomerase activity and telomere length in cultured human fetal fibroblasts. This supports a narrowly described cell-model research context, not a clinical product claim [2].
Current scientific understanding
The cited AEDG work is in vitro. Human reports involving Epithalamin examined a different, compositionally complex extract and cannot establish efficacy, safety, longevity effects, dosage, or interchangeability for synthetic Epithalon [2,3].
No medicinal authorization or human-use status is inferred. Claims from Epithalamin publications must not be transferred to this synthetic AEDG catalogue material.
Technical comparison
| Aspect | This catalogue material | Comparator |
|---|---|---|
| Identity | Synthetic, sequence-defined AEDG tetrapeptide, subject to batch-form confirmation | Epithalamin: biologically derived pineal extract with a non-equivalent composition |
| Structural distinction | Defined four-residue sequence | Complex extract rather than a single sequence-defined tetrapeptide |
| Analytical implication | Verify intact mass, sequence, salt, purity and assay for each catalogue strength | Extract characterization cannot substitute for AEDG peptide identity testing |
Quality and testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution’s approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] PubChem. Epithalon: structure and registry record.
- [2] Khavinson et al. AEDG, telomerase activity and telomere elongation in human fibroblast cultures (2003).
- [3] Khavinson et al. Clinical report concerning Epithalamin, a distinct pineal preparation (2011).
Frequently Asked Questions
Do the CAS number and PubChem CID apply to every batch form?
Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.
What does an analytical purity result mean?
It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution’s risk assessment. Use only storage and stability information linked to the exact material form and batch.





评价
目前还没有评价