NAD+ is supplied as a catalogued research material in 1000 mg.
NAD+ is an oxidized dinucleotide coenzyme, not a peptide. Public formula and mass records vary with protonation, and supplied materials may be salts or hydrates; the exact batch form must therefore govern identifier selection [1,2].
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | Nicotinamide adenine dinucleotide, Coenzyme I, DPN, Cozymase |
| Material category | Coenzyme / Metabolic |
| Sequence | Nicotinamide adenine dinucleotide |
| Molecular formula | C21H27N7O14P2 |
| Average molecular mass | 663.43 g/mol |
| CAS Registry Number | 53-84-9 |
| PubChem CID | CID 925 |
| Structural features | A dinucleotide consisting of two nucleosides (adenosine and nicotinamide riboside) joined by a pyrophosphate bridge. The nicotinamide moiety carries a positive charge. |
| Appearance | White to off-white lyophilised powder |
| Solubility | Freely soluble in water. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.
A pivotal coenzyme found in all living cells, involved in redox reactions, carrying electrons from one reaction to another. It functions as an oxidizing agent, being reduced to NADH.
Research background and published evidence
Published research
NAD+ is used as a cofactor or analyte in enzyme, redox, sirtuin and ADP-ribosylation assays and in analytical studies of nicotinamide nucleotide metabolism [2,3].
Current scientific understanding
Biochemical cofactor function and extracellular supply do not by themselves demonstrate cellular uptake or restoration of intracellular NAD+ pools. Assay literature does not establish human safety, efficacy or performance of this catalogue batch.
NAD+, NADH, free-acid/protonation records and sodium or other salts are analytically distinct and must not share unqualified masses or identifiers.
Technical comparison
| Aspect | This catalogue material | Comparator |
|---|---|---|
| Identity | Catalogue oxidized NAD+ material, with exact protonation and salt form requiring batch confirmation | Reduced nicotinamide adenine dinucleotide, NADH |
| Structural distinction | Oxidized nicotinamide redox state | Reduced nicotinamide redox state with a distinct composition and spectral response |
| Analytical implication | Confirm oxidation state, protonation, counter-ion, hydration and analyte content | NADH-specific mass and absorbance behavior must be measured separately |
Quality and testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution’s approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] PubChem. NAD(+), CID 5893.
- [2] KEGG Compound C00003. NAD+.
- [3] Imai et al. Sir2 as an NAD-dependent deacetylase linking metabolism and transcription. Nature (2000).
Frequently Asked Questions
Do the CAS number and PubChem CID apply to every batch form?
Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.
What does an analytical purity result mean?
It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution’s risk assessment. Use only storage and stability information linked to the exact material form and batch.
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